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Unsupervised Medical-Image Registration

An unsupervised VoxelMorph-based deep model for 3D liver MRI image registration, trained without ground-truth alignments.

Python PyTorch VoxelMorph Medical Imaging

Overview

An unsupervised deep learning model for 3D liver MRI image registration, built on the VoxelMorph architecture during MSc research at Otto-Von-Guericke University. The model learns a deformation field directly from unlabelled scan pairs, removing the need for manually annotated ground-truth alignments.

Key Features

  • Preprocessing pipeline that normalizes and resamples scan volumes to centre liver and tumour regions
  • Unsupervised VoxelMorph-based registration network trained without ground-truth deformation fields
  • Evaluation against Jaccard and Dice overlap metrics on held-out liver volumes

Results

Achieved a Jaccard coefficient of 91.44 and a Dice score of 93.27 on 3D liver MRI registration.